The term "Klondike Schist" describes metamorphosed igneous and sedimentary rocks first described from the Klondike area and later from south central Yukon. This paper describes the geology and chemistry of selected iron and base metal occurrences in Klondike Schist and proposes a model to assist further exploration for and evaluation of this type of mineralization. Four mineralized occurrences were examined in 1978, three on the northeast side of Tintina Fault in the Pelly Mountains - Fire Lake, North Lakes and Wolverine Lake and one southwest of the Tintina Fault, the Boundary prospect west of Dawson.