Draft technical document guidelines for Canadian drinking water quality - Antimony: Health considerations, derivation of health-based value

There are limited data on the toxicological effects of antimony in humans. The majority of the human data in the literature come from the reported side effects observed during therapeutic applications of antimony-based drugs (antimonials). Side effects observed following therapeutic-level doses include GI tract distress, cardiotoxicity, pancreatitis, hepatotoxicity and nephrotoxicity (Hepburn et al., 1994; Oliveira et al., 2009, 2011; Mlika et al., 2012; Wise et al., 2012). Although these studies provide useful insight into the potential effects following antimony exposure, the relevance of these reported effects following environmental exposures is uncertain due to the poor absorption of antimony compounds.

Données et ressources

Info additionnelle

Champ Valeur
Dernière modification avril 17, 2026, 17:47 (TU)
Créé le avril 17, 2026, 17:47 (TU)
criticality_level []
geographic_scope []
open_canada_collection publication
open_canada_date_published 2021-09-17 00:00:00
open_canada_keywords {"en": ["Draft", "technical document guidelines", "Canadian", "drinking water quality", "Antimony", "Health considerations", "derivation", "health-based value", "Absorption", "Distribution", "Metabolism", "Elimination", "Health effects", "Hepatotoxicity", "Gastrointestinal effects", "health-based value", "(HBV)"], "fr": ["Ébauche", "document technique lignes directrices", "Canadien", "qualité de l'eau potable", "Antimoine", "Considérations relatives à la santé", "dérivation", "valeur basée sur la santé", "Absorption", "Distribution", "Métabolisme", "Élimination", "Effets sur la santé", "Hépatotoxicité", "Effets gastro-intestinaux", "valeur basée sur la santé", "(VHB)"]}
open_canada_subject ["health_and_safety"]
sensitivity_level unrestricted
title_fr Recommandations pour la qualité de l’eau potable au Canada – Antimoine : Considérations relatives à la santé, calcul de la valeur
update_frequency as_needed