Cumulative effects of municipal effluent and parasite infection in yellow perch

Multiple metabolic, immune and reproductive effects have been reported in fish residing in effluent-impacted sites. Natural stressors such as parasites also have been shown to impact the responses of organisms to chronic exposure to municipal effluent in the St. Lawrence River (Quebec, Canada). In order to comprehensively evaluate the cumulative impacts of anthropogenic and natural stressors on the health of yellow perch, differential mRNA transcription profiles were examined in juvenile females collected from effluent-impacted and upstream sites with low or high infection levels of the larval trematode Apophallus brevis. Transcriptomics was used to identify biological pathways associated with environmental exposure. Overall, results indicated that juvenile yellow perch responded strongly to combined parasite and effluent exposure, suggesting cumulative effects on immune responses, inflammation and lipid metabolism mediated by retinoid receptors. The present study highlight the importance of using a comprehensive approach combining transcriptomics and endpoints measured at higher levels of biological organization to better understand cumulative risks of contaminants and pathogens in aquatic ecosystems.

Data and Resources

Additional Info

Field Value
Last Updated January 16, 2026, 20:46 (UTC)
Created January 16, 2026, 20:46 (UTC)
contains_pii non
crisis_categories Fortes pluies
criticality_level Faible
data_formats CSV; HTML
fair_openness Level 2 - Machine-readable
geographic_scope Québec
sensitivity_level Faible
source_inventaire Inventaire_W
source_url https://open.canada.ca/data/en/dataset/7776fa66-6bef-4bae-9168-9ddebf64b668
subject nature_and_environment
update_frequency as_needed
year_most_recent 2021-07-29 14:41:21.936000
year_start 2019-08-28 17:24:13.126000