Communities in east Hudson Bay and James Bay are concerned about ecosystem changes observed in recent decades, particularly related to sea-ice conditions, and also about potential impacts of contaminants from long-range atmospheric transport and regional human activities. The Arctic Eider Society’s Community-Driven Research Network (CDRN) was established to measure and better understand large-scale cumulative environmental impacts in east Hudson Bay and James Bay. Building on CDRN collaborations and activities in five communities (Sanikiluaq, Kuujjuaraapik, Inukjuak, Umiujaq, Chisasibi), this Northern Contaminants Program (NCP) community-based project generated new information on metal bioaccumulation that provide a regionally integrated perspective on metal exposure in the marine environment of east Hudson Bay and James Bay.