Biosafety Directive for Human Immunodeficiency Virus (HIV) and Human T-cell Lymphotropic Virus Type 1 (HTLV-1)

The human immunodeficiency virus (HIV) and the human T-cell lymphotropic virus type 1 (HTLV-1) are examples of RG3 pathogens where the pathogen risk and CL assessments have been revisited by the Agency in conjunction with HIV/HTLV specialists based on current risks associated with activities involving these pathogens. It has been determined that HIV & HTLV-1 can be safely handled at CL2/CL2-Ag with specific additional operational requirements (see Section 4.0). This Biosafety Directive is intended to provide a comprehensive overview of the risk assessment outcomes, subsequent CL decisions, and considerations that have been made for those working with HIV and HTLV-1. The Biosafety Directive for HIV and HTLV-1 is to be used in conjunction with the CBSG.

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Additional Info

Field	Value
Last Updated	April 17, 2026, 19:17 (UTC)
Created	April 17, 2026, 19:17 (UTC)
criticality_level	[]
geographic_scope	[]
open_canada_collection	publication
open_canada_date_published	2014-02-01 00:00:00
open_canada_keywords	{"fr": ["directive", "matière", "biosécurité", "virus de l’immunodéficience humaine", "vih", "virus", "t-lymphotrope", "humain", "type 1", "htlv-1", "agents pathogènes", "groupes de risque", "virus de l’immunodéficience humaine", "vih", "facteurs de risque", "virus t-lymphotrope humain", "type 1", "htlv-1", "facteurs", "risque", "biosécurité", "exigence", "opérationnelle", "supplémentaire", "in vitro", "culture", "exigence", "opérationnelle", "supplémentaire", "exigence opérationnelle", "supplémentaire"], "en": ["pathogen", "risk groups", "human immunodeficiency virus", "hiv", "description", "risk factors", "human t-cell", "lymphotropic virus", "type 1", "htlv-1", "containment", "level", "requirements", "cbsg", "containment zone", "containment level", "cl", "determination", "operational requirements", "activities", "in vivo", "biosafety", "directive", "human", "immunodeficiency", "virus", "hiv", "t-cell", "type 1", "htlv-1"]}
open_canada_subject	["health_and_safety"]
sensitivity_level	unrestricted
title_fr	Directive en matière de biosécurité portant sur le virus de l’immunodéficience humaine (VIH) et le virus T-lymphotrope humain de type 1 (HTLV-1)
update_frequency	unknown