Toxicity of the pharmaceuticals finasteride and melengestrol acetate to the freshwater mussels Lampsilis siliquoidea and Lampsilis fasciola

The toxicity of pharmaceuticals finasteride (FIN) and melengestrol acetate (MGA) was assessed in freshwater mussels, including an acute (48 h) aqueous tests with glochidia from Lampsilis siliquoidea, a sub-chronic (14 days) sediment test with gravid female Lampsilis fasciola, and chronic (21 and 28 days) sediment tests with juvenile L. siliquoidea. Glochidia viability was assessed in the 48 hour test; behaviour and glochidia viability were assessed in the 14 day test; and survival and burial was assessed in the 21 and 28 day tests.

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Additional Info

Field	Value
Last Updated	April 17, 2026, 19:14 (UTC)
Created	April 17, 2026, 19:14 (UTC)
contact_person	{}
criticality_level	[]
data_dictionary	[]
geographic_scope	["0"]
open_canada_collection	primary
open_canada_date_published	2021-11-25 00:00:00
open_canada_keywords	{"fr": ["moules d’eau douce", "Lampsilis siliquoidea", "sédiment", "toxicité", "pharmaceutiques", "Finastéride", "acétate de mélengestrol", "Lampsilis fasciola", "Le Bureau de l'évaluation et du contrôle des substances nouvelles (BECSN)", "Écosystème aquatique", "Eau douce", "Mollusque", "Biologie", "Toxicologie", "Produit chimique", "Épreuve biologique", "Sédiment", "Comportement"], "en": ["Freshwater mussel", "Lampsilis siliquoidea", "Sediment", "Toxicity", "Pharmaceuticals", "Finasteride", "Melengestrol acetate", "Lampsilis fasciola", "The New Substances Assessment and Control Bureau (NSACB)", "Aquatic ecosystems", "Fresh water", "Molluscs", "Biology", "Toxicology", "Chemicals", "Bioassay", "Sediments", "Behaviour"]}
open_canada_subject	["nature_and_environment"]
sensitivity_level	unrestricted
title_fr	Toxicité des produits pharmaceutiques finastéride et acétate de melengestrol pour les moules d’eau douce Lampsilis siliquoidea et Lampsilis fasciola
update_frequency	not_planned