In 2012 samples of raw influent and final effluent wastewater from five municipal wastewater treatment plants at various locations in Canada (sites to remain anonymous, designated in this data file as MH, OX, Q, TB, U). Also, leachate was collected from three landfill sites (sites to remain anonymous, designated in this data file as Q, TB and MH). The samples were analyzed for four artificial sweeteners (acesulfame, saccharin, cyclamate, sucralose), perchlorate, six anionic pesticides (glyphosate, 2,4-D, glufosinate, fosamine, MCPA, picloram) and a metabolite of glyphosate (AMPA). These data have not been published previously. Please see supporting document for methods for the analyses.