Summary Safety Review - Oral Retinoid Products - Assessing the Potential Risk of Impotence (erectile dysfunction)

Health Canada reviewed the potential risk of impotence (erectile dysfunction) with the use of oral retinoids because of a publication from the Netherlands that linked isotretinoin use with this side effect.Footnote1 Health Canada also reviewed the related evidence regarding all oral retinoids available in Canada. Impotence is when a man cannot achieve or maintain an erect penis for sexual activity.

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Additional Info

Field	Value
Last Updated	April 17, 2026, 17:32 (UTC)
Created	April 17, 2026, 17:32 (UTC)
criticality_level	[]
geographic_scope	[]
open_canada_collection	publication
open_canada_date_published	2017-05-18 00:00:00
open_canada_keywords	{"fr": ["Summary Safety Review", "Oral Retinoid Products", "assessing", "potential risk", "Impotence", "erectile dysfunction"], "en": ["Summary Safety Review", "Oral Retinoid Products", "assessing", "potential risk", "Impotence", "erectile dysfunction"]}
open_canada_subject	["health_and_safety"]
sensitivity_level	unrestricted
title_fr	Résumé de l'examen de l'innocuité - Rétinoïdes oraux - Évaluation du risque potentiel d'impuissance (dysfonction érectile)
update_frequency	as_needed