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URL: https://open.canada.ca/data/en/dataset/2156f8ee-a118-4652-9fdd-cb1dff18526f
After receiving two Canadian case reports involving canagliflozin, Health Canada reviewed the potential risk of PRES in patients treated with SGLT2 inhibitors who have developed DKA. SGLT2 inhibitors have been linked to an increased risk of DKA, which is a serious complication of diabetes. Posterior reversible encephalopathy syndrome is a rare condition which can affect the brain and is characterized by sudden changes in the nervous system including headaches, confusion, seizures, and vision trouble. It can develop in association with many conditions, such as severe infection or DKA, and drugs. When PRES is caused by a drug, it is important to stop the use of the drug as soon as possible to avoid complications.
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Additional Information
| Field | Value |
|---|---|
| Data last updated | January 16, 2026 |
| Metadata last updated | January 16, 2026 |
| Created | January 16, 2026 |
| Format | HTML |
| License | License not specified |
| Datastore active | False |
| Has views | False |
| Id | b4bef298-2c1e-4c90-8436-bebf1c348929 |
| Package id | 9b6eface-ab00-41b7-81be-a60ea56f1fc9 |
| Position | 0 |
| State | active |